Fig. 1

a NanoSight analysis measurements of sizes and concentrations of extracellular vesicles (EVs) secreted by human bone marrow-derived mesenchymal stem cells (hBM-MSCs). Representative graph shows the results of particle concentration and their size measurements. NTA analysis of this sample revealed two populations of EVs with peak diameter of 105 and 365 nm. b The Western blot analysis of EVs isolated from hBM-MSCs. EVs do not express calnexin, which is the membrane marker expressed on hBM-MSCs