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Table 1 Clinical features of patients and controls

From: Regulatory impairment in untreated Parkinson’s disease is not restricted to Tregs: other regulatory populations are also involved

 ControlPDP value
Socio-demographic and clinical characteristics
 Age at inclusion¢55.59 ± 10.2260.81 ± 10.230.064
 Male:female ratio^54:4656:44
 Body mass index (BMI)¢26.85 ± 3.8927.52 ± 4.540.549
 Symptom duration (years)¢NA2.90 ± 3.14
 Tremoric:akinetic ratio^NA59.4:53.1
Clinical scales¢
 Hoehn & YahrNA2.17 ± 0.88
 UPDRS I0.72 ± 0.982.50 ± 1.60< 0.0001***
 UPDRS II0.32 ± 0.8913.28 ± 6.56< 0.0001***
 UPDRS III1.72 ± 3.7135.68 ± 18.29< 0.0001***
 UPDRS IV0 ± 00 ± 0> 0.999
 Total UPDRS2.77 ± 4.0551.59 ± 25.13< 0.0001***
 Schwab-England scale99.54 ± 2.1376.59 ± 22.55< 0.0001***
 Beck’s depression test5.54 ± 6.2411.50 ± 8.000.003**
Non-motor symptoms^
 SialorrheaNA25
 Sleep disturbanceNA50
 HyposmiaNA25
 DepressionNA50
 FallsNA25
Comorbidities^
 Diabetes mellitus type 213.612.50.999
 Hypertension9.137.50.029*
 Dyslipidemia012.50.141
 Depressive disorder3.16.250.557
  1. ¢Values are expressed as mean ± SD
  2. ^Values are expressed as percentage of subjects
  3. *P < 0.05 is considered as significant
  4. ** P < 0.005 is considered as significant
  5. ***P < 0.0005 is considered as significant