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Table 4 Levels of human CD4 T helper cells in PD patients and healthy controls

From: Regulatory impairment in untreated Parkinson’s disease is not restricted to Tregs: other regulatory populations are also involved

CD4 cell subset

Control¢

PD¢

P value

CD4+

 

17.27 ± 7.96

13.76 ± 7.05

0.003**

 Th1

CD4+Tbet+IFN-γ+

1.98 ± 2.32

1.63 ± 1.30

0.733

CD4+Tbet+TNF−α+

3.27 ± 2.94

1.83 ± 1.62

0.165

 Th2

CD4+Gata-3+IL-13+

3.49 ± 5.32

4.94 ± 7 .21

0.537

CD4+Gata-3+IL-4+

2.43 ± 3.71

2.45 ± 2.93

0.455

 Th17

CD4+Ror-γ+IL-17α+

1.47 ± 2.16

0.98 ± 0.78

0.412

  1. ¢Values are expressed as mean ± SD
  2. *P < 0.05 is consider as significant
  3. **P < 0.005 is consider as significant
  4. CD4+ cells were determined as described in the “Material and methods” section for T helper cells
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Journal of Neuroinflammation

ISSN: 1742-2094