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Table 4 Levels of human CD4 T helper cells in PD patients and healthy controls

From: Regulatory impairment in untreated Parkinson’s disease is not restricted to Tregs: other regulatory populations are also involved

CD4 cell subsetControl¢PD¢P value
CD4+ 17.27 ± 7.9613.76 ± 7.050.003**
 Th1CD4+Tbet+IFN-γ+1.98 ± 2.321.63 ± 1.300.733
CD4+Tbet+TNF−α+3.27 ± 2.941.83 ± 1.620.165
 Th2CD4+Gata-3+IL-13+3.49 ± 5.324.94 ± 7 .210.537
CD4+Gata-3+IL-4+2.43 ± 3.712.45 ± 2.930.455
 Th17CD4+Ror-γ+IL-17α+1.47 ± 2.160.98 ± 0.780.412
  1. ¢Values are expressed as mean ± SD
  2. *P < 0.05 is consider as significant
  3. **P < 0.005 is consider as significant
  4. CD4+ cells were determined as described in the “Material and methods” section for T helper cells