Fig. 1
Experimental study design for acute and chronic fDTH-EAE models. a Rats in group A were studied with magnetic resonance imaging (MRI) on day 13 and with 18F-FOL or 11C-PBR28 positron emission tomography/computed tomography (PET/CT) on day 14 followed by ex vivo analyses. b Rats in group B were studied in both acute and chronic phases with MRI, 18F-FOL, or 11C-PBR28 PET/CT, plus ex vivo analyses at the end of the study. BCG = Bacillus Calmette-Guérin, TB = Mycobacterium tuberculosis, CFA = complete Freund’s adjuvant