Fig. 2
18F-FOL autoradiography with corresponding immunohistochemistry and histology of fDTH-EAE rat brains in acute and chronic phases with quantitative data. a Representative ex vivo 18F-FOL autoradiographs, anti-FR-β and anti-CD68 immunohistochemical staining, and H&E and Luxol Fast Blue (LFB) histological staining. The low-power scale bar is 2 mm, and the high-power scale bar is 50 μm. Quantification of b 18F-FOL autoradiography data and c demyelination from LFB staining. *P < 0.05. Error bars denote standard deviation. White asterisk in the H&E staining denotes the intracranial injection site to induce EAE