Table 1 Characteristics of the studied animals
Group A | Group B | ||
|---|---|---|---|
fDTH-EAE Days 13/14 | fDTH-EAE Days 13/14 | fDTH-EAE Days 89/90 | |
Animals (total n) | 10 | 10 | |
Weight (g) | 431 ± 24 | 455 ± 20 | 502 ± 49 |
Lesion area (mm2) | 0.061 ± 0.027 | ND | 1.3 ± 0.51 |
18F-FOL | |||
PET/CT (n) | 5 | 10 | 6 |
Brain autoradiography (n) | 5 | ND | 4 |
11C-PBR28 | |||
PET/CT (n) | 5 | 3 | 4 |
Brain autoradiography (n) | 5 | ND | 3 |
MRI | 10 | 10 | 10 |
Histology/immunohistochemistry | |||
H&E (n) | 10 | ND | 9 |
Anti-FR-β (n) | 10 | ND | 8 |
Anti-CD68 (n) | 10 | ND | 8 |
Anti-iNOS (n) | 10 | ND | 8 |
Anti-MRC-1 (n) | 9 | ND | 8 |
LFB (n) | 10 | ND | 9 |