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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Neuronal maturation reduces the type I IFN response to orthobunyavirus infection and leads to increased apoptosis of human neurons

Fig. 7

The type I interferon (IFN) response to LACV in neural progenitors and committed neurons. Expression of interferon-stimulated gene (ISG, upper section) type I IFN signaling and effector transcripts in the mock and LACV cells from COs that underwent single-cell transcriptome analysis. The same 7 clusters that were identified in Fig. 5 are shown and are segregated into the mock (red) and LACV (blue) samples. Increasing expression of each transcript is illustrated according to the deepening shade of either red for mock or blue for LACV. The proportion of cells expressing each transcript within the cluster are indicated by the size of the dot (scales at the bottom)

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