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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: The effects of n-6 polyunsaturated fatty acid deprivation on the inflammatory gene response to lipopolysaccharide in the mouse hippocampus

Fig. 4

Genes driving enrichment of inflammation-associated gene expression categories at day 1 and day 3 post-LPS administration in the n-6 PUFA deprived and adequate fed mice. a Gfap, glial fibrillary acidic protein. b Ccl 12, chemokine(C-Cmotif) ligand 12. c Irf7, interferon regulatory factor 7. d Ifitm3, interferon-induced transmembrane protein 3. e Ly6a, lymphocytic antigen 6 complex, locus A. f Fcgr1, Fc receptor IgG high affinity 1 gamma polypeptide. g Fcgr3, Fc receptor IgG, low affinity III. h Stat1, signal transducer and activator of transcription 1. i Lgals9, lectin, galactose binding, soluble 9. j B2m, beta-2 microglobulin. k C1qa, complement component 1 q sub component, alpha polypeptide. l C1qb, complement component 1 q sub component, beta polypeptide. m Trem2, triggering receptor expressed on myeloid cells 2. n Csf1r, colony stimulating factor 1 receptor. o Ang|Rnase4, angiogenin, 5|ribonuclease, RNase A family 4. p Ctss, cathepsin S. q Apod, apolipoprotein D. r Ighm, immunoglobulin heavy constant mu. s MHC l: H2-Q5, histocompatibility 2, Q region locus 5. t Hadha, hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (tri functional protein), alpha subunit. Gene names are provided with common name and abbreviated gene name in brackets. Bars represent means ± standard error of the mean, n = 3 mice per group. Major histocompatibility complex (MHC). Baseline refers to non-surgery; 1 and 3 refers to day 1 and day 3 post-LPS administration

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