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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Proteomic analysis of cerebrospinal fluid extracellular vesicles reveals synaptic injury, inflammation, and stress response markers in HIV patients with cognitive impairment

Fig. 3

Proteins associated with exosomes, cellular components, and biological processes are abundant in CSF EV fractions. a CSF EV fractions are enriched with exosomal proteins compared to EV-depleted CSF. Comparative abundance of proteins related to b neurons, astrocytes, myeloid cells, oligodendrocytes, endothelial cells, epithelial cells, blood-brain barrier (BBB), and choroid plexus (CP) and c biological processes including immune responses, inflammation, stress responses, and mitochondrial functions in EV fractions and EV-depleted CSF. Bar graphs show the number of total peptide counts for individual proteins among all EV fractions and EV-depleted CSF

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