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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Paclitaxel-activated astrocytes produce mechanical allodynia in mice by releasing tumor necrosis factor-α and stromal-derived cell factor 1

Fig. 4

Paclitaxel and TNF-α induce different expression of cytokines in cultured astrocytes. a, b Quantitative transcriptional analyses of GFAP, glutamate transporters (GLAST and GLT-1), and cytokines (TNF-α, IL-6, IL-1β) and chemokines in cultured astrocytes after exposure to vehicle control (24 h), paclitaxel (6 h and 24 h), or TNF-α (24 h) (*P < 0.05 compared to vehicle, t test, n = 4–5 per group). c TNF-α expression, revealed by ELISA analysis, in primary cultures of astrocytes after exposure to paclitaxel (6 h and 24 h) (*P < 0.05 compared to vehicle, t test, n = 4 per group)

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Journal of Neuroinflammation

ISSN: 1742-2094