Fig. 5
From: Nav1.6 promotes inflammation and neuronal degeneration in a mouse model of multiple sclerosis
The axonal pathology is improved in optic nerves with reduced Nav1.6 levels. Representative ultra-thin transversal sections of optic nerves were obtained from control non-EAE-treated/uninjected mice (a, −EAE/−AAVCre), EAE-treated/uninjected (b, +EAE/−AAVCre), and EAE-treated/AAV2Cre-injected (c, +EAE/+AAVCre). Images in b and c are of retinas from the same animal. Ax, axolytic; *, demyelinating. Scale bar, 5 μm