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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Anti-neuroinflammation ameliorates systemic inflammation-induced mitochondrial DNA impairment in the nucleus of the solitary tract and cardiovascular reflex dysfunction

Fig. 1

Peritoneal infusion with LPS disturbed blood pressure, heart rate, and baroreflex sensitivity in young Sprague-Dawley (SD) rats. The changes in a systolic blood pressure (SBP), b heart rate (HR), c the ratio of the power density of the low-frequency (LF) component to high-frequency (HF) component of the systolic blood pressure spectrum, and d baroreflex effectiveness index (BEI) after peritoneal infusion with saline or LPS for 7 days with additional intracisternal (IC) infusion of saline, PTX or mino. Values are the mean ± SEM of 12 to 15 animals in each group. ***P < 0.001 vs the control (C) group, and #P < 0.05, ##P < 0.01, ###P < 0.001 vs the LPS group according to post hoc Tukey’s multiple range analysis. C, control, infused with saline; L, LPS, lipopolysaccharides; mino, minocycline; PTX, pentoxifylline

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Journal of Neuroinflammation

ISSN: 1742-2094