Fig. 1
From: IL-33 deficiency causes persistent inflammation and severe neurodegeneration in retinal detachment
Retinal detachment (RD) and photoreceptor degeneration followed the injection of sodium hyaluronate. Two microliters of sodium hyaluronate was injected into the subretinal space to detach the neuroretina from RPE. a Representative photograph showing retinal detachment immediately following the injection of sodium hyaluronate. Arrow, detached retina. b, c Fundus image showing retinal damage at day 7 (b) and day 28 (c) post-RD. Arrow, detached area; arrowhead, non-detached area. d SD-OCT showing detached (arrow) and non-detached area (arrowhead) in the same eye at day 28 post-RD. Photoreceptor layer is thinner in the detached area (arrow). e, f Histology showing the intact photoreceptor cells and segments in normal ocular section (e) and detached retina (f, arrow, photoreceptor and segment loss) at day 28 post-RD. Scale bar, 100 μm