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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Elamipretide (SS-31) improves mitochondrial dysfunction, synaptic and memory impairment induced by lipopolysaccharide in mice

Fig. 4

Protective effects of elamipretide (SS-31) on mitochondrial dysfunction induced by LPS in the mouse hippocampus. a Representative fluorescence intensity images of J-aggregates (Cy3) and JC-1 monomers (FITC) from hippocampal mitochondria in each group. The MMP level b and ATP production c in the hippocampus were measured immediately after samples were prepared from each group. Scale bars: 20 μm, Data are expressed as the mean ± SE (n = 6). **P < 0.01, ***P < 0.001 vs. CON group. #P < 0.05 vs. LPS group. SS-31 elamipretide, aCSF artificial cerebrospinal fluid, LPS lipopolysaccharide, SE standard error

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