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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Elamipretide (SS-31) improves mitochondrial dysfunction, synaptic and memory impairment induced by lipopolysaccharide in mice

Fig. 5

Elamipretide (SS-31) attenuated oxidative stress and the inflammatory response induced by LPS in the mouse hippocampus. a Reactive oxygen species (ROS) levels, b malondialdehyde (MDA) levels, and c superoxide dismutase (SOD) activities. ELISA assays of IL-6 d and TNF-α e levels in samples of the hippocampus. Scale bars: 20 μm, Data are expressed as the mean ± SE (n = 6–8). **P < 0.01, ***P < 0.001 vs. CON group; #P < 0.05, ##P < 0.01 vs. LPS group. SS-31 elamipretide, aCSF artificial cerebrospinal fluid, LPS lipopolysaccharide, SE standard error

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