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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Stress-induced microglial activation occurs through β-adrenergic receptor: noradrenaline as a key neurotransmitter in microglial activation

Fig. 6

A Iba1 IHC for CTRL (a, b), 1 h RS (c, d), and 2 h RS (e, f) after saline and β-blocker treatment, respectively. B High-power photomicrographs of Iba1 IHC for CTRL (a, b), 1 h RS (c, d), and 2 h RS (e, f) after saline and β-blocker treatment, respectively. Scale bar: 200 μm in low-power and 20 μm in high-power photos. C Circles, 20 μm from the soma, used for Scholl analysis are shown on Iba1-ir microglia at CTRL, 1 h RS, and 2 h RS after saline and β-blocker treatment, respectively. Scale bar: 20 μm. D Double-immunofluorescence staining with OX-42 (green) and Iba1 (red) in the HT, with upper panes at CTRL (β-blocker), and 1h RS (β-blocker), respectively. Scale bar: 20 μm. E No immunoreactivity to cleaved caspase-3 was found in the HT at 1h RS after propranolol treatment. Scale Bar: 20 μm

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Journal of Neuroinflammation

ISSN: 1742-2094