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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Stress-induced microglial activation occurs through β-adrenergic receptor: noradrenaline as a key neurotransmitter in microglial activation

Fig. 7

a, b Histograms demonstrating the cell size (upper) and cell count (lower) of Iba1-ir microglia (a) and GFAP-ir astrocytes (b) in the HT at CTRL, 1 h RS, 2 h RS, and 4 h RS, respectively, as compared to β-blocker treatment. c Real-time PCR analysis for IL-1β and IL-18 mRNAs. GAPDH mRNA was used as an internal control. An arbitrary value of 1 was assigned to the levels of IL-1β/GAPDH and IL-18/GAPDH under control conditions. The asterisks indicate a statistical difference between saline-treated and β-blocker-treated rats at each time point (*p < 0.05, **p < 0.01, n = 4)

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