Fig. 4
From: Genetic deletion of soluble epoxide hydrolase delays the progression of Alzheimer’s disease
a–j Loss of function of sEH decreases Aβ deposition in APP/PS1 Tg mice. a Brain tissue sections from 6-month-old APP/PS1 Tg and APP/PS1 Tg/sEH−∕− mice were immunostained with anti-Aβ and FITC-conjugated secondary antibody, and then the FITC intensity was assessed. Scale bar = 100 μm. b–j Western blot analysis of protein levels of oligomer (oligo) or monomer (mono) Aβ, BACE1, βCTF, ABCA1, LRP-1, apoE, and α-tubulin. Data are mean ± SEM from 8 mice in each group. *P < 0.05 vs. APP/PS1 Tg mice