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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Intrastriatal injection of preformed alpha-synuclein fibrils alters central and peripheral immune cell profiles in non-transgenic mice

Fig. 6

Alterations in percentage and total number of immune cells in the inguinal lymph node of PFF α-syn mice. Mononuclear immune cells from the inguinal lymph node were isolated from PFF α-syn or monomer α-syn mice at 5 months p.i. (n = 6 per group). a Plots show the numbers of total CD45+ leukocytes, CD19+ B cells, T cells (CD4+ and CD8+ T cells), CD11b+ macrophage, Ly6+ neutrophils, and NK1.1+ NK cells (blue: monomer α-syn; red: PFF α-syn). b Plots show the percentages of CD19+ B cells, CD4+ T cells, CD8+ T cells, CD11b+ macrophage, Ly6+ neutrophils, and NK1.1+ NK cells under the CD45+ gated leukocytes. Data represent mean ± SEM. Data represent mean ± SEM. *p < 0.05 or **p < 0.01, n.s.; not significant, Student’s t test

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Journal of Neuroinflammation

ISSN: 1742-2094