From: Anti-MOG autoantibodies pathogenicity in children and macaques demyelinating diseases
Demographic | ADS n = 27 | MS n = 10 | ADEM n = 5 | ADS MOG+ n = 6 | Others n = 6 |
---|---|---|---|---|---|
Sex M/F | 6: 21 | 1: 9 | 1: 4 | 2: 4 | 2: 4 |
Age years, mean, SD | 11.1 ± 4.1 | 12.8 ± 1.9 | 7.9 ± 5.5 | 8.9 ± 4.3 | 13.1 ± 2.6 |
EDSS mean, SD | 0.7 ± 1.2 | 1.4 ± 1.6 | 0 ± 0 | 0.7 ± 0.8 | 0 ± 0 |
CSF | |||||
Cell > 10 mm3 | 11 | 3 | 2 | 5 | 1 |
Prot > 0.5 g/dL | 7 | 3 | 1 | 2 | 1 |
OCB (n = 22) | 8 | 6/10 | 1/3 | 1/5 | 0/4 |
FU years, mean, SD | 3.0 ± 1.6 | 3.5 ± 1.2 | 3.2 ± 0.9 | 3.8 ± 2.3 | 1.3 ± 0.7 |
Anti-AQP4 | 0 | 0 | 0 | 0 | 0 |
Anti-MOG | 12 | 0 | 1 | 6 | 5 |