Fig. 2

The majority of the HDAC2 protein was colocalized with CaMKII⁺ neurons, and microglia were activated after LPS administration. a–c Representative images of coimmunostaining for HDAC2 and CaMKII, Iba1 or GFAP in the hippocampal CA1 region are shown (n = 3–4 sections from 4 mice, scale bar = 100 μm). d The majority of HDAC2 was colocalized with CaMKII rather than Iba1 or GFAP (n = 4). e The expression of Iba1 was significantly increased in the LPS group (n = 4). Data are presented as the mean ± S.E.M. ^*P < 0.05 and ^**P < 0.01