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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Lipopolysaccharide induces neuroinflammation in microglia by activating the MTOR pathway and downregulating Vps34 to inhibit autophagosome formation

Fig. 4

LPS inhibits autophagosome formation in N9 microglial cells by activating the PI3KI/AKT/MTOR pathway. Microglial cells were treated with 1 μg/mL LPS for the indicated times. The protein levels of PI3KI, p-AKT, AKT, p-MTOR, MTOR (a), p-p70S6K and p70S6K (e) were analyzed by western blotting and quantified (bd, f). Data are presented as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001 vs control

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