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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: CXCL12 is involved in α-synuclein-triggered neuroinflammation of Parkinson’s disease

Fig. 4

CXCL12/CXCR4 was involved in α-synuclein-induced microglial migration. a The migration of BV-2 cells towards CXCL12 was measured by Transwell assay, and AMD3100 was added to the upper chambers to block the interaction between CXCL12 and CXCR4. b The migration of BV-2 cells induced by α-synuclein was observed with or without pretreatment with a TLR4 inhibitor (TAK242) or an NF-κB inhibitor (PDTC). The data are shown as the mean ± SEM from three independent experiments. *p < 0.05

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