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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Monocarboxylate transporter 1 promotes classical microglial activation and pro-inflammatory effect via 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3

Fig. 6

Intracerebroventricular injection of lactate ameliorated LPS-induced sickness behavior in mice. a–c Quantification of mice total distance, reared times, and resting times by open field tests after intraperitoneal injection of LPS and intraventricular injection of L-lactate (n = 8 per group and errors represent S.E.M, **p and ##p < 0.01; two-way ANOVA followed by post hoc)

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