Fig. 8

Modulation of intracellular signaling pathways after resistance exercise. a, e Representative blots of Akt, JNK, ERK, and Bax/Bcl-2 in the frontal cortex and hippocampus. b–d The analysis of protein expression in the frontal cortex. f–h The analysis of protein expression in the hippocampus. Band intensity was normalized to that of GAPDH. For Akt, GSK-3β, JNK, and ERK, the phosphorylated forms were normalized to their total forms. (unpaired Student’s t tests, n = 6, *p < 0.05, **p < 0.01, compared to sedentary mice. Data present as mean ± SEM). SED sedentary, RE resistance exercise