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Table 2 The analysis of genotype and allele distribution on PD cases and controls

From: Association of LAG3 genetic variation with an increased risk of PD in Chinese female population

SNPModelsPDControlORp
rs951818Dominant ((CC + CA)/AA)552/77460/721.122 (0.795–1.583)0.570
Recessive (CC/(CA + AA))282/347213/3191.217 (0.963–1.538)0.113
Allele (C/A)834/424673/3911.143 (0.963–1.356)0.137
 FemaleDominant ((CC + CA)/AA)218/33154/401.716 (1.036–2.843)0.048
Recessive (CC/(CA + AA))118/13359/1352.030 (1.369–3.010)0.001
Allele (C/A)336/166213/1751.663 (1.266–2.185)0.000
 MaleDominant ((CC + CA)/AA)334/44306/320.794 (0.491–1.284)0.412
Recessive (CC/(CA + AA))164/214154/1840.916 (0.682–1.230)0.610
Allele (C/A)498/258460/2160.906 (0.727–1.130)0.414
rs1922452Dominant ((AA+AG)/GG)555/79466/590.889 (0.621–1.274)0.583
Recessive (AA/(AG + GG))282/352208/3170.945 (0.703–1.271)0.108
Allele (A/G)837/431674/3761.083 (0.913–1.286)0.384
 FemaleDominant ((AA+AG)/GG)222/34165/250.989 (0.568–1.722)1
Recessive (AA/(AG + GG))118/13858/1321.975 (1.311–2.888)0.001
Allele (A/G)340/172223/1571.392 (1.058–1.831)0.022
 MaleDominant ((AA+AG)/GG)333/45301/340.836 (0.521–1.340)0.531
Recessive (AA/(AG + GG))164/214150/1851.221 (0.965–1.544)0.766
Allele (A/G)497/259451/2190.932 (0.747–1.162)0.568
rs870849Dominant ((CC + CT)/TT)615/16513/110.824 (0.379–1.792)0.698
Recessive (CC/(CT + TT))441/189373/1510.945 (0.732–1.218)0.708
Allele (C/T)1056/205886/1620.942 (0.752–1.179)0.641
 FemaleDominant ((CC + CT)/TT)246/4184/51.671 (0.443–6.310)0.508
Recessive (CC/(CT + TT))186/64136/531.133 (0.740–1.734)0.643
Allele (C/T)432/68320/581.151 (0.788–1.682)0.527
 MaleDominant ((CC + CT)/TT)369/12329/60.561 (0.208–1.511)0.339
Recessive (CC/(CT + TT))255/125237/980.844 (0.614–1.160)0.333
Allele (C/T)624/137566/1040.837 (0.633–1.106)0.229
  1. PD Parkinson’s disease, OR odds ratio, 95% CI 95% confidence interval. p value obtained by continuity corrected χ2 test. The genotype of rs19922452-AA and rs951818-CC was found to be significantly higher in female PD patients than in controls, respectively (rs951818, OR = 2.03, p = 0.001; rs19922452, OR = 1.975, p = 0.001)