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Fig. 10 | Journal of Neuroinflammation

Fig. 10

From: Chronic dry eye induced corneal hypersensitivity, neuroinflammatory responses, and synaptic plasticity in the mouse trigeminal brainstem

Fig. 10

GFAP and Iba1 immunoreactivity and expression of neuronal and inflammatory markers in the ipsilateral TBSC at d21. a GFAP immunoreactivity from sham and DED mice. Right panels show magnification of the dashed line inset. Scale bars = 100 μm. b Quantification of GFAP immunoreactivity (percentage of the area immunostained with GFAP). c Iba1 immunoreactivity from sham and DED mice. Right panels show magnification of the dashed line inset. Scale bars = 100 μm. d Quantification of Iba1 immunoreactivity (percentage of the area immunostained with Iba1). e RT-qPCR analysis of the ipsilateral TBSC of sham and DED mice at d21 post-surgery. *P < 0.05 and **P < 0.01 relative to the sham group (n = 5–16 per group). Results are expressed as the mean ± SEM

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