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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Chronic dry eye induced corneal hypersensitivity, neuroinflammatory responses, and synaptic plasticity in the mouse trigeminal brainstem

Fig. 8

Time course of the spontaneous activity of the ciliary nerve in sham and DED mice. a Electrophysiological traces illustrating the extracellular activity of the ciliary nerve fiber at d7, d14, and d21 in sham and DED mice; time scale = 0.5 s. b Electrophysiological traces illustrating the extracellular activity of the ciliary nerve fiber at d21 in sham and DED mice; time scale = 1 s and 0.05 s. c Histograms showing the mean value of the spontaneous firing frequency of ciliary nerves in both groups of animals. *P < 0.05, ***P < 0.001, and #P < 0.05 relative to the sham group (naïve animals (before surgery = d0) n = 6, sham animals: n = 5 at d7, n = 5 at d14, and n = 7 at d21; DED animals n = 8 at d7, n = 5 at d14, and n = 8 at d21). Results are expressed as the mean ± SEM from d7 to d21 post-surgery

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