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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Wnt canonical pathway activator TWS119 drives microglial anti-inflammatory activation and facilitates neurological recovery following experimental stroke

Fig. 2

TWS119 improved post-stroke neurological function. CatWalk test (a–c), Adhesive Removal test (d, e), Accelerated Rotarod test (f) and mNSS (g) were performed between vehicle group and TWS119 group at day 1, 7, 14 and 21 after stroke. a-e TWS119 treatment, as opposed to saline injection, accelerated LF functional recovery. f TWS119 mice displayed better performance in Accelerated Rotarod test compared with vehicle mice. g TWS119 mice had lower mNSS compared with vehicle mice. LF, left forelimb, mNSS, modified neurological severity scores. (n = 8 per group, * P < 0.05, ** P < 0.01, *** P < 0.001, N.S = no statistical difference)

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Journal of Neuroinflammation

ISSN: 1742-2094