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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Wnt canonical pathway activator TWS119 drives microglial anti-inflammatory activation and facilitates neurological recovery following experimental stroke

Fig. 4

TWS119 stimulated post-stroke neural plasticity. a Representative image of coronal sections labeled with GAP43 (axon marker), and PSD95 (postsynaptic structure marker). b TWS119 mice showed a higher density of GAP43+ puncta and PSD95+ puncta at day 21 after stroke compared with vehicle mice. c Representative image of coronal sections labeled with SMI312 (neurofilament marker), and Synaptophysin (presynaptic structure marker). d TWS119 also upregulated the density of SMI312+ puncta or Synaptophysin+ puncta at day 21 after stroke. (n = 6 per group, * P < 0.05, ** P < 0.01)

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Journal of Neuroinflammation

ISSN: 1742-2094