Skip to main content

Table 1 Differentially expressed genes identified in each genotype by genome-wide transcriptome analysis. TR number of transcript-reads by microarray, aFC absolute fold-change, DEG differentially expressed gene (mapped ID + statistically significant by FC and p cutoffs)

From: Loss of amyloid precursor protein exacerbates early inflammation in Niemann-Pick disease type C

 

Npc1+/+/App−/−

Npc1−/−/App+/+

Npc1−/−/App−/−

TR (aFC > 1.5)

6269

3967

7132

TR (p < 0.05)

1534

684

3359

DEG (FC + p)

891

431

1973

DEG (up)

418

252

1265

DEG (down)

473

179

708