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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: TGFβRI antagonist inhibits HIV-1 Nef-induced CC chemokine family ligand 2 (CCL2) in the brain and prevents spatial learning impairment

Fig. 8

Blocking TGFβR1 with SD208 decreases CD163 expression in rats infused with astrocytes expressing Nef. a Representative tissue sections immunostained for macrophage marker, CD163. Nef+placebo (upper panel), n = 4 and Nef+SD208 (lower panel), n = 5. b Densitometric analysis was used to quantify the intensity of CD163 staining, **p < 0.01. Scale bar 100 μM

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