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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: TGFβRI antagonist inhibits HIV-1 Nef-induced CC chemokine family ligand 2 (CCL2) in the brain and prevents spatial learning impairment

Fig. 9

Blocking TGFβR1 with SD208 decreases GFAP expression in rats infused with astrocytes expressing Nef. a Representative tissue sections immunostained for astrocyte activation marker, GFAP. Nef+placebo (left panel), n = 5, and Nef+SD208 (right panel), n = 3. b Densitometric analysis was used to quantify the intensity of GFAP staining, *p < 0.03. Scale bar 100 μM

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