Skip to main content
Fig. 10 | Journal of Neuroinflammation

Fig. 10

From: URB597 protects against NLRP3 inflammasome activation by inhibiting autophagy dysfunction in a rat model of chronic cerebral hypoperfusion

Fig. 10

Effects of URB, autophagy inhibitor 3-MA, lysosome inhibitor CQ and ROS scavenger NAC on CCH-induced ROS accumulation. a Representative DHE fluorescence staining for ROS in the hippocampal CA1 region (scale bars = 50 μm). b Relative level of ROS (ratio of the sham group). The ROS level in the sham group is normalized to 1. Data are expressed as mean ± SEM (n = 5). *P < 0.05 versus sham group. **P < 0.05 versus BCCAo group

Back to article page