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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Microglial depletion and repopulation in brain slice culture normalizes sensitized proinflammatory signaling

Fig. 5

Microglia repopulate following removal of PLX3397. Iba-1 immunohistochemistry showing that Iba-1+ microglia were depleted after 10 days of treatment of PLX3397, with subsequent repopulation across 14 days after PLX3397 cessation. Quantification of Iba-1 microglia found greater than 95% depletion of microglia which were repopulated progressively back to control levels after 14 days

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