Fig. 1

Upregulation of KCa3.1 channels and Iba1 in the brains of PD mouse model. a Western blot analysis of SNpc lysates from control and MPTP-induced PD mouse model analyzed by antibodies to TH, GFAP, Iba1, and KCa3.1. Data represent the mean ± SEM (n = 3). Western blot was repeated three times and showed similar results; *p < 0.05, unpaired, two-tailed Student’s t test compared with control. b Double immunofluorescence analysis of KCa3.1 (green) levels in microglia (Iba1, red) of control and MPTP group mouse SNpc. DAPI (blue) was used to label nuclei. Scale bar 50 μm