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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Time course of neuropathological events in hyperhomocysteinemic amyloid depositing mice reveals early neuroinflammatory changes that precede amyloid changes and cerebrovascular events

Fig. 4

Microhemorrhages increase at 14 weeks on the HHcy diet in APP/PS1 mice. a Representative image of Prussian blue-positive microhemorrhage in the frontal cortex. Magnification = × 200. Scale bar = 50 μm, arrows indicate microhemorrhages. Quantification of the mean number of microhemorrhages per section from T2* MRI (b) or Prussian blue histology (c). ** indicates P < 0.01 compared to APP/PS1 mice on control diet for that time point

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