Fig. 5From: Time course of neuropathological events in hyperhomocysteinemic amyloid depositing mice reveals early neuroinflammatory changes that precede amyloid changes and cerebrovascular eventsHHcy redistributes amyloid to the vasculature at 14 weeks on diet in the APP/PS1 mice despite no effect of HHcy on total Abeta levels. a–f Representative images of Congo red staining in the frontal cortex of APP/PS1 mice on control diet or HHcy diet for 10, 14, or 18 weeks are shown. Magnification = × 200X. Scale bar in A = 50 μm for all images. Black arrows indicate amyloid around a vessel. g-h Quantification of percent positive stain in the frontal cortex (g) and hippocampus (h). * indicates P < 0.05, ** indicates P < 0.01 compared to APP/PS1 mice on control diet at that time pointBack to article page