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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: KS23, a novel peptide derived from adiponectin, inhibits retinal inflammation and downregulates the proportions of Th1 and Th17 cells during experimental autoimmune uveitis

Fig. 1

KS23 ameliorates the progression of EAU in a dose-dependent manner. B10RIII mice were induced with EAU using R161 and were sacrificed 28 days after immunization. KS23 (5 mg/kg, 10 mg/kg, or 15 mg/kg) was intraperitoneally injected every second day. n = 6 per group. a The mean clinical scores recorded every 2 days, from day 2 to day 28 after treatment with KS23. b, c Histological analysis of hematoxylin and eosin-stained retinal sections showing the extent of inflammation and the mean pathological scores. Scale bar 200 μm. Results are shown as means ± SD. **p < 0.01, ***p < 0.001; ns, non-significant

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Journal of Neuroinflammation

ISSN: 1742-2094