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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: KS23, a novel peptide derived from adiponectin, inhibits retinal inflammation and downregulates the proportions of Th1 and Th17 cells during experimental autoimmune uveitis

Fig. 5

KS23 inhibits the proportions of peripheral Th1 and Th17 subsets. Groups of B10RIII mice were immunized with R161 to induce EAU and treated with PBS, KS23, or TQ23. n = 6 per group. Flow cytometric analysis of Th1(a) (IFN-γ+T-bet+) and Th17 (c) cells (IL-17A+RORγt+) in CD3+CD4+ T cells, isolated from the spleens of mice on day 21 after EAU induction. The proportion of Th1 (b) and Th17 (d) cells in the splenic cells of mice on day 21 after EAU induction. Results are shown as means ± SD. *p < 0.05, **p < 0.01, ***p < 0.001; ns, non-significant

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Journal of Neuroinflammation

ISSN: 1742-2094