Fig. 3

Upregulation of glial markers 24 h after experimental meningitis induction in the PFC and hippocampus. Western blot analysis of the tissue protein levels of glial and neuronal markers. Quantification of immunoblot data using the densitometric analysis of each protein was carried out using Image Lab™ software (Bio-Rad, CA, USA). Representative immunoblots and quantification of CD 11B, IBA-1, GFAP, Oligo, NeuN, C1q, and β-tubulin in the PFC (a–g) and hippocampus (h–n). The values for all protein levels were normalized to those of β-tubulin. The results are expressed as the mean ± SEM for n = 4–5 rats. *P < 0.05 compared to controls