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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Dysregulation of BDNF/TrkB signaling mediated by NMDAR/Ca2+/calpain might contribute to postoperative cognitive dysfunction in aging mice

Fig. 4

Increased hippocampal levels of IL-1β and IL-6 after anesthesia and surgery were detected on day 8 post-surgery, which were attenuated by MEM treatment. a Representative Western blots of IL-1β in the hippocampus. β-tubulin was included as loading control. b Quantitative analysis of IL-1β levels. c Representative Western blots of IL-6 in the hippocampus. β-tubulin was included as loading control. d Quantitative analysis of IL-6 levels. Data are presented as the mean ± SEM (n = 6). *p < 0.05 compared to the con + veh group (**p < 0.01, ***p < 0.001), #p < 0.05 compared to the sur + veh group (##p < 0.01, ###p < 0.001)

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