Skip to main content
Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Dysregulation of BDNF/TrkB signaling mediated by NMDAR/Ca2+/calpain might contribute to postoperative cognitive dysfunction in aging mice

Fig. 7

Increased levels of markers associated with cell apoptosis were attenuated by MEM or MDL-28170 treatment on day 1 post-surgery. a Representative Western blots of bax in the hippocampus. β-tubulin was included as loading control. b Quantitative analysis of bax. c Representative Western blots of bcl-2. β-tubulin was included as loading control. d Quantitative analysis of bcl-2 levels. e Representative Western blots of FL-caspase-3 and cleaved caspase-3 in the hippocampus. β-tubulin was included as loading control. f Quantitative analysis of cleaved caspase-3 and FL-caspase-3 levels. g Representative western-blots of GluN2A. β-tubulin was included as loading control. h Quantitative analysis of GluN2A levels. i Representative Western blots of GluN2B. β-tubulin was included as loading control. j Quantitative analysis of GluN2B levels. Data are presented as the mean ± SEM (n = 6). *p < 0.05 compared to the con+ veh group (**p < 0.01, ***P < 0.001), #p < 0.05 compared to the sur + veh group (##p < 0.01, ###p < 0.001)

Back to article page