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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Clozapine reduces infiltration into the CNS by targeting migration in experimental autoimmune encephalomyelitis

Fig. 6

cAMP expression is altered by clozapine in splenocytes. Splenocytes (a, b) or sorted monocytes (c, d) were left untreated or stimulated with forskolin, CCL2 or CCL5 and clozapine in a single treatment or with different combinations and cAMP accumulation was measured with in the cells. Two technical replicates in three independent experiments per treatment group. *p < 0.0332, **p < 0.021, ***p < 0.0002 and by two-way ANOVA with Tukey’s multiple comparisons test

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