Fig. 1
From: Dimethyl fumarate alleviates the nitroglycerin (NTG)-induced migraine in mice
Effects of DMF treatment on NTG-induced damage. The neuronal damage in Sp5C neurons was observed in NTG-injured mice (B, B1 and F, F1) respect to control and control + sumatriptan group (respectively A, A1; C, C1; and F, F1). The treatment with DMF, mainly at the dose of 100 mg/kg, significantly restored a large number of trigeminal neurons in Sp5C area (E, E1). Data are means ± SEM of ten mice for each group. One-way ANOVA followed by Bonferroni post-test. ND not detectable. ***p < 0.001 vs. Sham; #p < 0.05 and ###p < 0.001vs. NTG, °°°p < 0.001 vs Sham. F value = 60.88