Fig. 3

Correlation of serum neurofilament light chain (sNfL) concentrations upon admission with the Hughes Functional Score (HFS) calculated a on admission (HFS*a) with a Spearman’s correlation coefficient r_s of 0.52 (p = 0.005) and b at nadir (HFS*n) with an r_s of 0.59 (p = 0.001). Each dot in the scatter plot represents a sample, the line the estimated linear regression. c sNfL levels on admission in association with HFS at discharge (HFS*d) as a dichotomised outcome HFS = 1 and HFS ≥ 2. Each dot represents a single individual. Box plots indicate median and IQR with whiskers extending 1.5 times the IQR