Fig. 5
From: Systemic microbial TLR2 agonists induce neurodegeneration in Alzheimer’s disease mice
5xFAD cortex contains higher number of TLR2+ microglia. a A 2-fold higher amount of CD11b + microglia was isolated from the cortex of 5xFAD as compared with wt mice. b–d FACS analysis of TLR2 expression in isolated CD11b + microglia from wt and 5xFAD mice. There was a 6-fold increase in the fraction of TLR2-expressing microglia in 5xFAD mice (b, c, *p = 0.0002). Mean fluorescence intensity (MFI) was 20% higher in TLR2-expressing microglia from 5xFAD as compared with wt mice (d, *p = 0.0006)