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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Suppression of histone deacetylases by SAHA relieves bone cancer pain in rats via inhibiting activation of glial cells in spinal dorsal horn and dorsal root ganglia

Fig. 5

TCI-induced upregulation of HDAC1 and HDAC2 in the dorsal root ganglia following TCI or SNL. a Immunofluorescent staining of HDAC1 and HDAC2 in the dorsal root ganglia at various time points (Sham, POD 7 and POD 14 for TCI; Sham and POD 14 for SNL). Scale bar = 100 μm. b Double immunofluorescent staining showing the co-localization of HDAC1/HDAC2 (green) and satellite glial cells (GFAP, red) at various time points (Sham, POD 7, and POD 14 for TCI; Sham and POD 14 for SNL). Scale bar = 100 μm (outside); 50 μm (inside)

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