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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Suppression of histone deacetylases by SAHA relieves bone cancer pain in rats via inhibiting activation of glial cells in spinal dorsal horn and dorsal root ganglia

Fig. 8

The effect of SAHA administration on bone destruction following TCI. a 2D representative MicroCT images of trabecular bone microarchitecture. b Quantitative analysis of the BMD in tibia of the TCI + vehicle and the TCI + SAHA group (n = 4). Data are expressed as the mean ± SEM. Representative images of HE staining showing cancer cell infiltration (cells within the dotted lines) and bone resorption pits (arrows) on trabecular surface in tibial marrow cavity of the TCI + vehicle (b (i, ii)) and TCI + SAHA (b (ii, iii)) group. Original magnification: 100 (upper row), 200 (bottom row)

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Journal of Neuroinflammation

ISSN: 1742-2094