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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: Suppression of histone deacetylases by SAHA relieves bone cancer pain in rats via inhibiting activation of glial cells in spinal dorsal horn and dorsal root ganglia

Fig. 9

The inhibitory effects of SAHA on GSK3β activities in the spinal dorsal horn and dorsal root ganglia on POD 21. a Representative bands and quantitative analysis of p-GSK3β and GSK3β in the spinal dorsal horn of the Sham + vehicle, the TCI + vehicle, the TCI + SAHA and the Sham + SAHA group (n = 4). Analysis was based on the mean gray values and normalized to β-actin. b Representative bands and quantitative analysis of p-GSK3β and GSK3β in the dorsal root ganglia of the Sham + vehicle, the TCI + vehicle, the TCI + SAHA and the Sham + SAHA group (n = 4). Analysis was based on the mean gray values and normalized to β-actin. Data are expressed as the mean ± SEM. *p < 0.05 versus the Sham + vehicle group and #p < 0.05, ##p < 0.01 versus the TCI + vehicle group

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